I'm not exactly sure what draws me to this one. Is it that strange question or the fact that the narrator finds it the most interesting thing to happen to him?
"Are you a child of DNA?"
Rakesh was affronted; if he'd considered this to be information that any stranger wandering by had a right to know, it would have been included in his précis. After a moment's reflection, though, his indignation gave way to curiosity. The stranger was either being deliberately offensive, or had a very good reason for asking. Either way, this was the most interesting thing that had happened to him all day.
Incandescence by Greg Egan
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The Amalgam spans nearly the entire galaxy, and is composed of innumerable beings from a wild variety of races, some human or near it, some entirely other. The one place that they cannot go is the bulge, the bright, hot center of the galaxy. There dwell the Aloof, who for millions of years have deflected any and all attempts to communicate with or visit them. So when Rakesh is offered an opportunity to travel within their sphere, in search of a lost race, he cannot turn it down. Roi is a member of that lost race, which is not only lost to the Amalgam, but lost to itself. In their world, there is but toil, and history and science are luxuries that they can ill afford. Rakesh's journey will take him across millennia and light years. Roi's will take her across vistas of learning and discovery just as vast.